Clarity™
Major and Minor BCR-ABL Mutation Quantification Kit
Clarity™
Major and Minor BCR-ABL Mutation Quantification Kit
Reproducibility
Precise quantification of b2a2, b3a2 or e1a2 mutation abundance
Ease of Use
Low hands-on-time, compatible with most conventional thermal cyclers
High Sensitivity
Detect as low as 0.01% of b2a2, b3a2 or e1a2 mutant DNA
Manufactured in Singapore under ISO 13485
High Throughput Analysis
Analyze up to 96 reactions in 4 hours
Product Performance
.
The Clarity™ Major BCR-ABL and Minor BCR-ABL Mutation Quantification Kit detected at least 0.01% mutant cDNA against a high background of more than 35,000 copies of total ABL cDNA. In addition, excellent linearity is achieved (R2 >0.999) from 100% down to 0.01% for the respective mutant fractions (Figures 1 & 2).
Technology | Digital PCR |
Target Sequence | b2a2, b3a2 or e1a2 and ABL cDNA |
Sensitivity (LOD) | 0.01% mutation |
Time to Result | < 4 h |
Specimen Type | Whole Blood |
Reporting Format | Ratio of mutant (b2a2, b3a2 or e1a2) versus total ABL expression |
Instrument Tested | Clarity™ digital PCR system (Cat. No. 10001) |
Additional Material Required | Clarity™ consumables package (Cat. No. 10011) |
Detection Channels | FAM (b2a2, b3a2 or e1a2 cDNA), HEX (ABL cDNA) |
Kit Storage | -20°C, avoid repeated freezing and thawing of kit contents |
Product name | Description | Cat. No. |
---|---|---|
Clarity™ EGFR T790M Mutation Quantification Kit | 48 reactions | 10016 |
Clarity™ Epstein-Barr Virus Quantification Kit | 96 reactions | 10017 |
Clarity™ Hepatitis B Virus Quantification Kit | 96 reactions | 10018 |
Clarity™ EGFR L858R Mutation Quantification Kit | 48 reactions | 10019 |
Clarity™ IDH2 Mutation Quantification Kit | 48 reactions | 10021 |
Clarity™ Major BCR-ABL Mutation Quantification Kit | 96 reactions | 10022 |
Clarity™ Minor BCR-ABL Mutation Quantification Kit | 96 reactions | 10023 |